Principles of Anatomy & Physiology

Discussions on The Human Body

A joint a day keeps the doctor away?

Are you sick of hearing someone nagging you about letting go of your pot pasttime? Have you been hearing a lot of negative things about the use of marijuana lately? Would you like to know what the real deal is behind the use of this infamous drug? Then read on because you’re in for a surprise.

One of the saddest things in North America is the lack of clinical trials on marijuana use. Many other countries in the world have already performed such tests in order to destroy myths about this drug, which has been in use for thousands of years… mainly for medicinal purposes.

The data from previous studies, published in numerous books and scholarly journals, covered such matters as marijuana’s effects on the brain, lungs, immune and reproductive systems; its impact on personality, developmental and motivational states; and its addictive potential.

Although these studies did not answer all remaining questions about marijuana toxicity, they generally supported the idea that marijuana was a relatively safe drug — not totally free from potential harm, but unlikely to create serious harm for most individual users or society.

The following list will hopefully demystify several myths about marijuana use and help answer a lot of serious questions:

health risk myths & realities

Marijuana Overdose
There is no existing evidence of anyone dying of a marijuana overdose. Tests performed on mice have shown that the ratio of cannabinoids (the chemicals in marijuana that make you high) necessary for overdose to the amount necessary for intoxication is 40,000:1.

For comparison’s sake, that ratio for alcohol is generally between 4:1 and 10:1. Alcohol overdoses claim approximately 5,000 casualties yearly, but marijuana overdoses kill no one as far as any official reports.

Brain Damage
Marijuana is psychoactive because it stimulates certain brain receptors, but it does not produce toxins that kill them (like alcohol), and it does not wear them out as other drugs may. There is no evidence that marijuana use causes brain damage. Studies performed on actual human populations will confirm these results, even for chronic marijuana users (up to 18 joints per day) after many years of use.

In fact, following the publication of two 1977 JAMA studies, the American Medical Association (AMA) officially announced its support for the decriminalization of marijuana.

In reality, marijuana has the effect of slightly increasing alpha-wave activity in your brain. Alpha waves are generally associated with meditative and relaxed states, which are, in turn, often associated with human creativity.

Memory
Marijuana does impair short-term memory, but only during intoxication. Although the authoritative studies on marijuana use seem to agree that there is no residual impairment following intoxication, persistent impairment of short-term memory has been noted in chronic marijuana smokers, up to 6 and 12 weeks following abstinence.

What other myths have been going around about smoking a doobie ?

Heart Problems
It is accepted in medical circles today that marijuana use causes no evident long-term cardiovascular problems for normal persons. Marijuana smoking, however, does cause changes in the heart and body’s circulation characteristic of stress, which may complicate preexisting cardiovascular problems like hypertension, cerebrovascular disease, and coronary atherosclerosis. Marijuana’s effects on blood pressure are complex and inconsistent as of yet.

Hormones
Chronic marijuana use has not been found to alter testosterone or other sex hormone levels. In contrast, heavy alcohol use is known to lower these same testosterone levels.

Reproductive Damage
No trustworthy study has ever shown that marijuana use damages the reproductive system, or causes chromosome breakage. Studies of actual human populations have failed to demonstrate that marijuana adversely affects the reproductive system. Claims that marijuana use may impair hormone production, menstrual cycles, or fertility in females are both unproven and unfounded.

The Immune System
Studies in which lab rats were injected with extremely large quantities of THC (the active compound in marijuana) have found that marijuana (in such unrealistically huge quantities) does have an “immunosuppressive effect” in those lab rats, in that it temporarily shuts off certain cells in the liver called lymphocytes and macrophages. These macrophages are useful in fighting off bacterial, not viral, infections.

But this is only for the duration of intoxication. There also exists some evidence that marijuana metabolites remain in the lungs for up to seven months after smoking has ceased, possibly affecting the immune system of the lungs (but not by turning the cells off).

This said, doctors and researchers are still not sure that the immune system is actually negatively affected in realistic situations since there are no numbers to support the idea. In fact, three studies s
Expensive? You need to start buying in bulk brotha.

How does the structure of the stomach function?

a few more questions:

Which organelle in plant cells enables them to make food?
Do bacteria have organs?explain your answer.
How does the skeletal system interact with the digestive system?
How does the skeletal system interact with the endocrine system?

answer what u can but only answer if u really know the answer

Neutrophil granulocytes as a trojan horse for leishmania?

I have read a review on how Leishmania parasites can use the neutrophil immune cells as temporary shelters, until the cells die and both cell and parasite are engulfed by a macrophage. Allowing the parasite to access its host cell undetected by the immune system.

My question is actually about alternative pathways, assuming the parasite was not engulfed by a neutrophil but by a macrophage which detected the pathogen. A) would the parasite survive macrophage killing and how and B) would the infection take hold.

I have done some research into this and whilst finding lots of information on the first route of entry, i am having trouble finding papers or information on straight macrophage phagocytosis of leishmania as a route of entry.

If possible please link papers/sources
Thanks

anatomy question (respiratory system)?

1.) You have climbed the stairs going to the third floor of this building to get to your classroom. Then you sit quietly in the laboratory room listening to the class discussion and taking down notes. How does the respiratory system help maintain your body equilibrium with such different levels of physical activity?

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